Using several immunodiagnostic techniques, our researchers investigated in what forms cTnI and cTnT (as components of the troponin complexes) are present in the blood of patients with acute myocardial infarction. Based on the results the authors propose a scheme of the transformation of a full-size troponin complex into smaller units. This information could be used for designing an immunoassay that would allow for detecting all cTnI forms regardless of the time between blood sample and onset of the acute myocardial infarction thus improving the sensitivity of the troponin assay.