Thyroglobulin TechNotes

Thyroglobulin is a glycoprotein that is produced exclusively by the follicular cells of the thyroid. It is secreted into the follicular lumen, where it serves as a storage reservoir for the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is a protein dimer of 660 kDa in size, it has a high number (approximately 60) of disulfide bonds per monomer and 17 glycosylation sites (1). The production of thyroglobulin is stimulated by thyroid-stimulating hormone (TSH), intrathyroidal iodine deficiency, and the presence of thyroid-stimulating immunoglobulins.

Products: 

Cat# 2TG12cc: Thyroglobulin, antibody
Cat# 8TG52: Thyroglobulin
Cat# 8RTG4: Thyroglobulin, human, recombinant